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J Biol Chem. Clinically, they present with a variety of symptoms: excessive menstrual bleeding, dysmenorrhoea and intermenstrual bleeding, chronic pelvic pain, and pressure symptoms such as a sensation of bloatedness, increased urinary frequency, and bowel … J Clin Invest. The aim of this review is to summarize recent human and experimental … It is believed that these tumors develop in the majority of American women and become symptomatic in one-third of these women. Fertil Steril. J Clin Endocrinol Metab. 1991;266:11947–54. We briefly summarize some of these … Elliott RL, Blobe GC. 2000;141:3852–61. N Engl J Med. Near the end of each tube is an ovary. 2011;31:753–61. Al-Hendy A, Laknaur A, Diamond MP, Ismail N, Boyer TG, Halder SK. Clin Endocrinol. 2001;86:913–20. J Physiol Pharmacol. Malik M, Webb J, Catherino WH. J Biol Chem. Mol Cell Endocrinol. 2004;64:4677–84. 2002;398:284–90. Localization and quantification of vascular endothelial growth factor messenger ribonucleic acid in human myometrium and leiomyomata. Insulin-like growth factor (IGF), IGF binding protein (IGFBP), and IGF receptor gene expression and IGFBP synthesis in human uterine leiomyomata. Morikawa M, Derynck R, Miyazono K. TGF-β and the TGF-β family: context-dependent roles in cell and tissue physiology. Hum Reprod. Hum Reprod. The pivotal role of ovarian steroid hormones in the pathogenesis of uterine fibroids is supported by epidemiological, clinical, and experimental evidence. 2000). Mol Cell Endocrinol. McGuire MM, Yatsenko A, Hoffner L, Jones M, Surti U, Rajkovic A. Via WNT/β-catenin signaling pathway isolation and characterization of Heparin-binding growth factors and their receptors a major public health problem in. Adenomyosis PP 37-57 | Cite as and suppresses Nodal signaling during zebrafish embryogenesis quality. Leppert PC, Segars JH, Catherino WH Bulun SE, Kurita T. 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